{"id":56,"date":"2026-04-09T16:01:12","date_gmt":"2026-04-09T08:01:12","guid":{"rendered":"https:\/\/www.drzoe.cn\/?p=56"},"modified":"2026-04-09T16:13:43","modified_gmt":"2026-04-09T08:13:43","slug":"led%e5%85%89%e5%af%b9%e7%9a%ae%e8%82%a4%e7%9a%84%e5%bd%b1%e5%93%8d%ef%bc%9a%e7%a7%91%e5%ad%a6%e6%9c%ba%e5%88%b6%e4%b8%8e%e4%b8%b4%e5%ba%8a%e8%af%81%e6%8d%ae","status":"publish","type":"post","link":"https:\/\/www.drzoe.cn\/?p=56","title":{"rendered":"LED\u5149\u5bf9\u76ae\u80a4\u7684\u5f71\u54cd\uff1a\u79d1\u5b66\u673a\u5236\u4e0e\u4e34\u5e8a\u8bc1\u636e"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f15\u8a00<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LED\uff08\u53d1\u5149\u4e8c\u6781\u7ba1\uff09\u5149\u7597\u4f5c\u4e3a\u4e00\u79cd\u975e\u4fb5\u5165\u6027\u76ae\u80a4\u6cbb\u7597\u624b\u6bb5\uff0c\u8fd1\u5e74\u6765\u5728\u76ae\u80a4\u79d1\u548c\u7f8e\u5bb9\u9886\u57df\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u4e0d\u540c\u4e8e\u6fc0\u5149\u7684\u5f3a\u80fd\u91cf\u8f93\u51fa\uff0cLED\u5149\u7597\u4ee5\u4f4e\u80fd\u91cf\u3001\u975e\u70ed\u6548\u5e94\u7684\u65b9\u5f0f\u4f5c\u7528\u4e8e\u76ae\u80a4\uff0c\u8fd9\u79cd\u6280\u672f\u88ab\u79f0\u4e3a<strong>\u5149\u751f\u7269\u8c03\u8282\uff08Photobiomodulation, PBM\uff09<\/strong>\u6216\u4f4e\u5f3a\u5ea6\u5149\u7597\uff08Low-Level Light Therapy, LLLT\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u6587\u57fa\u4e8e\u73b0\u6709\u79d1\u5b66\u7814\u7a76\uff0c\u5ba2\u89c2\u68b3\u7406LED\u5149\u5bf9\u76ae\u80a4\u7684\u4f5c\u7528\u673a\u5236\u3001\u4e0d\u540c\u6ce2\u957f\u7684\u529f\u6548\u5dee\u5f02\u4ee5\u53ca\u4e34\u5e8a\u5e94\u7528\u8bc1\u636e\uff0c\u5e2e\u52a9\u8bfb\u8005\u5efa\u7acb\u79d1\u5b66\u8ba4\u77e5\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e00\u3001LED\u5149\u7597\u7684\u4f5c\u7528\u673a\u5236<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1.1 \u7ec6\u80de\u5c42\u9762\u7684\u5149\u5438\u6536<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LED\u5149\u7597\u7684\u6838\u5fc3\u673a\u5236\u5728\u4e8e<strong>\u7ec6\u80de\u8272\u7d20c\u6c27\u5316\u9176\uff08Cytochrome c Oxidase, CCO\uff09<\/strong>\u5bf9\u7279\u5b9a\u6ce2\u957f\u5149\u5b50\u7684\u5438\u6536\u3002CCO\u662f\u7ebf\u7c92\u4f53\u7535\u5b50\u4f20\u9012\u94fe\u7684\u7ec8\u7aef\u9176\uff0c\u8d1f\u8d23\u7ec6\u80de\u80fd\u91cf\uff08ATP\uff09\u7684\u4ea7\u751f\u3002\u5f53\u7279\u5b9a\u6ce2\u957f\u7684\u5149\uff08\u4e3b\u8981\u4e3a\u7ea2\u5149600-700nm\u548c\u8fd1\u7ea2\u5916\u5149700-1200nm\uff09\u88abCCO\u5438\u6536\u540e\uff0c\u4f1a\u4fc3\u8fdbATP\u5408\u6210\uff0c\u589e\u5f3a\u7ec6\u80de\u4ee3\u8c22\u6d3b\u6027\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">1.2 \u4fe1\u53f7\u901a\u8def\u7684\u6fc0\u6d3b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5149\u751f\u7269\u8c03\u8282\u4e0d\u4ec5\u9650\u4e8e\u80fd\u91cf\u4ee3\u8c22\u7684\u63d0\u5347\uff0c\u8fd8\u4f1a\u6fc0\u6d3b\u591a\u6761\u7ec6\u80de\u4fe1\u53f7\u901a\u8def\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TGF-\u03b2\u4fe1\u53f7\u901a\u8def<\/strong>\uff1a\u4fc3\u8fdb\u80f6\u539f\u86cb\u767d\u548c\u5f39\u6027\u86cb\u767d\u7684\u5408\u6210<\/li>\n\n\n\n<li><strong>PI3K\/AKT\u901a\u8def<\/strong>\uff1a\u8c03\u8282\u7ec6\u80de\u5b58\u6d3b\u3001\u589e\u6b96\u548c\u8fc1\u79fb<\/li>\n\n\n\n<li><strong>Nrf2\u901a\u8def<\/strong>\uff1a\u53d1\u6325\u6297\u6c27\u5316\u548c\u6297\u708e\u4f5c\u7528<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u8868\u660e\uff0c\u8fd9\u4e9b\u5206\u5b50\u5c42\u9762\u7684\u53d8\u5316\u6700\u7ec8\u8868\u73b0\u4e3a\u76ae\u80a4\u7ed3\u6784\u7684\u6539\u5584\u548c\u529f\u80fd\u7684\u589e\u5f3a\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e8c\u3001\u4e0d\u540c\u6ce2\u957fLED\u5149\u7684\u529f\u6548\u5dee\u5f02<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">2.1 \u7ea2\u5149\uff08620-700nm\uff09\uff1a\u6297\u8870\u8001\u4e0e\u4fee\u590d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e3b\u8981\u529f\u6548\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u523a\u6fc0\u6210\u7ea4\u7ef4\u7ec6\u80de\u589e\u6b96<\/li>\n\n\n\n<li>\u4fc3\u8fdbI\u578b\u548cIII\u578b\u80f6\u539f\u86cb\u767d\u5408\u6210<\/li>\n\n\n\n<li>\u6539\u5584\u76ae\u80a4\u5f39\u6027\u548c\u7d27\u81f4\u5ea6<\/li>\n\n\n\n<li>\u52a0\u901f\u4f24\u53e3\u6108\u5408<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e34\u5e8a\u8bc1\u636e\uff1a<\/strong><br>\u4e00\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7eb3\u5165\u4e86136\u540d\u53d7\u8bd5\u8005\uff0c\u63a5\u53d7\u7ea2\u5149\uff08633nm\uff09\u548c\u8fd1\u7ea2\u5916\u5149\uff08830nm\uff09\u8054\u5408\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u6cbb\u7597\u540e12\u5468\uff0c\u53d7\u8bd5\u8005\u9762\u90e8\u7ec6\u7eb9\u3001\u76ae\u80a4\u7c97\u7cd9\u5ea6\u663e\u8457\u6539\u5584\uff0c\u76ae\u80a4\u80f6\u539f\u86cb\u767d\u5bc6\u5ea6\u589e\u52a0\u3002\u53e6\u4e00\u9879\u4f53\u5916\u7814\u7a76\u8bc1\u5b9e\uff0c\u7ea2\u5149\u4e0e\u8fd1\u7ea2\u5916\u5149\u8054\u5408\u4f7f\u7528\u53ef\u4e0a\u8c03\u80f6\u539f\u86cb\u767d\u548c\u5f39\u6027\u86cb\u767d\u7684\u57fa\u56e0\u8868\u8fbe\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7136\u800c\uff0c\u9700\u8981\u6ce8\u610f\u7684\u662f\uff0c<strong>\u9ad8\u5242\u91cf\u7ea2\u5149\u53ef\u80fd\u4ea7\u751f\u6291\u5236\u6548\u5e94<\/strong>\u3002\u6709\u7814\u7a76\u53d1\u73b0\uff0c\u9ad8\u80fd\u91cf\u7ea2\u5149\u53cd\u800c\u53ef\u80fd\u6291\u5236\u6210\u7ea4\u7ef4\u7ec6\u80de\u589e\u6b96\u548c\u80f6\u539f\u86cb\u767d\u5408\u6210\uff0c\u63d0\u793a\u5242\u91cf\u53c2\u6570\u7684\u91cd\u8981\u6027\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2.2 \u84dd\u5149\uff08400-495nm\uff09\uff1a\u6297\u83cc\u4e0e\u63a7\u6cb9<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e3b\u8981\u529f\u6548\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6740\u706d\u75e4\u75ae\u4e19\u9178\u6746\u83cc\uff08<em>Cutibacterium acnes<\/em>\uff09<\/li>\n\n\n\n<li>\u51cf\u5c11\u76ae\u80a4\u708e\u75c7<\/li>\n\n\n\n<li>\u8c03\u8282\u76ae\u8102\u5206\u6ccc<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4f5c\u7528\u673a\u5236\uff1a<\/strong><br>\u75e4\u75ae\u4e19\u9178\u6746\u83cc\u4ea7\u751f\u7684\u5185\u6e90\u6027\u535f\u5549\uff08\u4e3b\u8981\u662f\u7caa\u535f\u5549III\uff09\u5728\u84dd\u5149\u7167\u5c04\u4e0b\u88ab\u6fc0\u6d3b\uff0c\u4ea7\u751f\u5355\u7ebf\u6001\u6c27\uff0c\u4ece\u800c\u6740\u706d\u7ec6\u83cc\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e34\u5e8a\u8bc1\u636e\uff1a<\/strong><br>\u4e00\u9879\u7cfb\u7edf\u8bc4\u4ef7\u548c\u835f\u8403\u5206\u6790\u7eb3\u5165\u4e86\u591a\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u7ed3\u679c\u663e\u793a\u84dd\u5149\u6cbb\u7597\u53ef\u663e\u8457\u51cf\u5c11\u708e\u75c7\u6027\u75e4\u75ae\u76ae\u635f\u6570\u91cf\uff0c\u7597\u6548\u4e0e\u53e3\u670d\u6297\u751f\u7d20\u76f8\u5f53\uff0c\u4e14\u65e0\u660e\u663e\u526f\u4f5c\u7528\u30022023\u5e74\u7684\u4e00\u9879\u52a8\u7269\u5b9e\u9a8c\u786e\u5b9a\u4e86\u84dd\u5149\u6cbb\u7597\u7684\u6700\u4f73\u53c2\u6570\u4e3a100 mW\/cm\u00b2\u7684\u529f\u7387\u5bc6\u5ea6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4f46\u9700\u6ce8\u610f\uff1a<\/strong> \u84dd\u5149\u5e76\u975e\u5bf9\u6240\u6709\u4eba\u90fd\u9002\u7528\u3002\u6709\u7814\u7a76\u6307\u51fa\uff0c\u84dd\u5149\u53ef\u80fd\u4ea7\u751f\u6c27\u5316\u5e94\u6fc0\uff0c\u5bf9\u76ae\u80a4\u9020\u6210\u6f5c\u5728\u635f\u4f24\uff0c\u5c24\u5176\u662f\u5728\u9ad8\u5242\u91cf\u66b4\u9732\u65f6\u3002\u6b64\u5916\uff0c\u84dd\u5149\u5bf9\u6df1\u5c42\u75e4\u75ae\u7684\u6548\u679c\u6709\u9650\uff0c\u4e3b\u8981\u4f5c\u7528\u4e8e\u76ae\u80a4\u8868\u9762\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2.3 \u9ec4\u5149\uff08570-590nm\uff09\u4e0e\u7eff\u5149\uff08520-560nm\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ec4\u5149\u548c\u7eff\u5149\u5728\u76ae\u80a4\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u7814\u7a76\u76f8\u5bf9\u8f83\u5c11\u3002\u521d\u6b65\u7814\u7a76\u8868\u660e\uff0c\u9ec4\u5149\u53ef\u80fd\u5177\u6709\u6297\u708e\u548c\u8212\u7f13\u4f5c\u7528\uff0c\u800c\u7eff\u5149\u53ef\u80fd\u5728\u6539\u5584\u8272\u7d20\u6c89\u7740\u65b9\u9762\u6709\u4e00\u5b9a\u6f5c\u529b\uff0c\u4f46<strong>\u9ad8\u8d28\u91cf\u4e34\u5e8a\u8bc1\u636e\u4ecd\u4e0d\u5145\u5206<\/strong>\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e09\u3001LED\u5149\u7597\u7684\u5b89\u5168\u6027\u4e0e\u5c40\u9650\u6027<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">3.1 \u5b89\u5168\u6027<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LED\u5149\u7597\u603b\u4f53\u4e0a\u88ab\u8ba4\u4e3a\u662f\u5b89\u5168\u7684\uff0c\u4e0d\u826f\u53cd\u5e94\u8f83\u5c11\u3002\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u5305\u62ec\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6682\u65f6\u6027\u7ea2\u6591<\/li>\n\n\n\n<li>\u76ae\u80a4\u5e72\u71e5<\/li>\n\n\n\n<li>\u5149\u654f\u611f\uff08\u7f55\u89c1\uff09<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e0e\u7d2b\u5916\u7ebf\u4e0d\u540c\uff0cLED\u5149\u7597<strong>\u4e0d\u5f15\u8d77DNA\u635f\u4f24<\/strong>\uff0c\u65e0\u5149\u81f4\u764c\u98ce\u9669\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3.2 \u5c40\u9650\u6027<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u7597\u6548\u4e2a\u4f53\u5dee\u5f02\u5927<\/strong>\uff1a\u4e0d\u540c\u80a4\u8d28\u3001\u5e74\u9f84\u3001\u5149\u635f\u4f24\u7a0b\u5ea6\u7684\u60a3\u8005\u53cd\u5e94\u5dee\u5f02\u663e\u8457<\/li>\n\n\n\n<li><strong>\u9700\u8981\u591a\u6b21\u6cbb\u7597<\/strong>\uff1a\u901a\u5e38\u9700\u8981\u6570\u5468\u81f3\u6570\u6708\u7684\u6301\u7eed\u6cbb\u7597\u624d\u80fd\u770b\u5230\u660e\u663e\u6548\u679c<\/li>\n\n\n\n<li><strong>\u5bb6\u7528\u8bbe\u5907\u529f\u7387\u9650\u5236<\/strong>\uff1a\u5bb6\u7528LED\u8bbe\u5907\u529f\u7387\u8fdc\u4f4e\u4e8e\u533b\u7528\u8bbe\u5907\uff0c\u7597\u6548\u53ef\u80fd\u6709\u9650<\/li>\n\n\n\n<li><strong>\u84dd\u5149\u7684\u53cc\u9762\u6027<\/strong>\uff1a\u867d\u7136\u6297\u83cc\uff0c\u4f46\u8fc7\u5ea6\u66b4\u9732\u53ef\u80fd\u52a0\u901f\u76ae\u80a4\u5149\u8001\u5316<\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u56db\u3001\u79d1\u5b66\u5171\u8bc6\u4e0e\u5efa\u8bae<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u57fa\u4e8e\u73b0\u6709\u8bc1\u636e\uff0c\u6211\u4eec\u53ef\u4ee5\u5f97\u51fa\u4ee5\u4e0b\u5ba2\u89c2\u7ed3\u8bba\uff1a<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2705 <strong>\u8bc1\u636e\u8f83\u5145\u5206\u7684\u5e94\u7528\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7ea2\u5149\/\u8fd1\u7ea2\u5916\u5149\u7528\u4e8e\u6539\u5584\u76ae\u80a4\u5149\u8001\u5316\u3001\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408<\/li>\n\n\n\n<li>\u84dd\u5149\u7528\u4e8e\u8f7b\u4e2d\u5ea6\u708e\u75c7\u6027\u75e4\u75ae\u7684\u8f85\u52a9\u6cbb\u7597<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u26a0\ufe0f <strong>\u8bc1\u636e\u6709\u9650\u6216\u5b58\u5728\u4e89\u8bae\u7684\u9886\u57df\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>LED\u5149\u7597\u5bf9\u76ae\u80a4\u8272\u7d20\u6c89\u7740\u7684\u5f71\u54cd<\/li>\n\n\n\n<li>\u7eff\u5149\u3001\u9ec4\u5149\u7684\u5177\u4f53\u529f\u6548<\/li>\n\n\n\n<li>\u5bb6\u7528\u8bbe\u5907\u7684\u957f\u671f\u6548\u679c<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e94\u3001\u603b\u7ed3<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LED\u5149\u7597\u4f5c\u4e3a\u4e00\u79cd\u975e\u4fb5\u5165\u6027\u76ae\u80a4\u6cbb\u7597\u624b\u6bb5\uff0c\u5728\u7279\u5b9a\u9002\u5e94\u75c7\u4e0a\u5c55\u73b0\u51fa\u826f\u597d\u7684\u5e94\u7528\u524d\u666f\u3002\u7136\u800c\uff0c\u6d88\u8d39\u8005\u5e94\u7406\u6027\u770b\u5f85\u76f8\u5173\u5ba3\u4f20\uff0c\u4e86\u89e3\u5176<strong>\u4f5c\u7528\u673a\u5236\u7684\u590d\u6742\u6027<\/strong>\u548c<strong>\u7597\u6548\u7684\u4e2a\u4f53\u5dee\u5f02\u6027<\/strong>\u3002\u9009\u62e9LED\u5149\u7597\u4ea7\u54c1\u65f6\uff0c\u5efa\u8bae\u5173\u6ce8\u8bbe\u5907\u7684\u6ce2\u957f\u53c2\u6570\u3001\u529f\u7387\u5bc6\u5ea6\u7b49\u6280\u672f\u6307\u6807\uff0c\u5e76\u5728\u4e13\u4e1a\u533b\u5e08\u6307\u5bfc\u4e0b\u4f7f\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u79d1\u5b66\u62a4\u80a4\u7684\u672c\u8d28\u662f<strong>\u57fa\u4e8e\u8bc1\u636e\u7684\u51b3\u7b56<\/strong>\uff0c\u800c\u975e\u76f2\u76ee\u8ffd\u968f\u6f6e\u6d41\u3002\u5e0c\u671b\u672c\u6587\u80fd\u5e2e\u52a9\u60a8\u5efa\u7acb\u5bf9LED\u5149\u7597\u7684\u79d1\u5b66\u8ba4\u77e5\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">: Avci P, Gupta A, Sadasivam M, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. <em>Seminars in Cutaneous Medicine and Surgery<\/em>. 2013;32(1):41-52. https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4126803\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: De Freitas LF, Hamblin MR. Proposed mechanisms of photobiomodulation or low-level light therapy. <em>IEEE Journal of Selected Topics in Quantum Electronics<\/em>. 2016;22(3):348-364. https:\/\/ieeexplore.ieee.org\/abstract\/document\/7488285\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Mamalis A, Siegel D, Jagdeo J. Visible red light emitting diode photobiomodulation for skin fibrosis: key molecular pathways. <em>Current Dermatology Reports<\/em>. 2016;5(2):132-139. https:\/\/link.springer.com\/article\/10.1007\/s13671-016-0141-x<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Chang H, Shen Q, Tan Y, et al. Red light promotes dermis-epidermis remodeling via TGF\u03b2 and AKT-mediated collagen dynamics in naturally aging mice. <em>Zoological Research<\/em>. 2025;46(2):396-410. https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12780493\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Hamblin MR. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. <em>AIMS Biophysics<\/em>. 2017;4(3):337-361. https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5523874\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Wunsch A, Matuschka K. A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase. <em>Photomedicine and Laser Surgery<\/em>. 2014;32(2):93-100. https:\/\/journals.sagepub.com\/doi\/abs\/10.1089\/pho.2013.3616<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Li WH, Seo IS, Kim B, et al. Low\u2010level red plus near infrared lights combination induces expressions of collagen and elastin in human skin in vitro. <em>International Journal of Cosmetic Science<\/em>. 2021;43(3):311-320. https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/ics.12698<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Mamalis A, Jagdeo J. The combination of resveratrol and high-fluence light emitting diode-red light produces synergistic photobotanical inhibition of fibroblast proliferation and collagen synthesis: a novel treatment for skin fibrosis. <em>Dermatologic Surgery<\/em>. 2017;43(1):115-124. https:\/\/journals.lww.com\/dermatologicsurgery\/fulltext\/2017\/01000\/The_Combination_of_Resveratrol_and_High_Fluence.12.aspx<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Dai T, Gupta A, Murray CK, et al. Blue light for infectious diseases: <em>Propionibacterium acnes<\/em>, <em>Helicobacter pylori<\/em>, and beyond? <em>Drug Resistance Updates<\/em>. 2012;15(4):223-236. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1368764612000465<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Scott AM, Stehlik P, Clark J, et al. Blue-light therapy for acne vulgaris: a systematic review and meta-analysis. <em>The Annals of Family Medicine<\/em>. 2019;17(6):545-553. https:\/\/www.annfammed.org\/content\/17\/6\/545.short<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Diogo MLG, Campos TM, Fonseca ESR, et al. Effect of blue light on acne vulgaris: a systematic review. <em>Sensors<\/em>. 2021;21(20):6943. https:\/\/www.mdpi.com\/1424-8220\/21\/20\/6943<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Nakayama E, Kushibiki T, Mayumi Y, et al. Optimal blue light irradiation conditions for the treatment of acne vulgaris in a mouse model. <em>Journal of Photochemistry and Photobiology B: Biology<\/em>. 2023;238:112585. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1011134423000052<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Bonnans M, Fouque L, Pelletier M, et al. Blue light: Friend or foe? <em>Journal of Photochemistry and Photobiology B: Biology<\/em>. 2020;211:112022. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1011134420304760<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Ngoc LTN, Moon JY, Lee YC. Utilization of light\u2010emitting diodes for skin therapy: Systematic review and meta\u2010analysis. <em>Photodermatology, Photoimmunology &amp; Photomedicine<\/em>. 2023;39(4):311-321. https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/phpp.12841<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Hern\u00e1ndez-Bule ML, Naharro-Rodr\u00edguez J, et al. Unlocking the power of light on the skin: a comprehensive review on photobiomodulation. <em>International Journal of Molecular Sciences<\/em>. 2024;25(8):4483. https:\/\/www.mdpi.com\/1422-0067\/25\/8\/4483<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">: Dompe C, Moncrieff L, Matys J, et al. Photobiomodulation\u2014underlying mechanism and clinical applications. <em>Journal of Clinical Medicine<\/em>. 2020;9(6):1724. https:\/\/www.mdpi.com\/2077-0383\/9\/6\/1724<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><em>\u672c\u6587\u4ec5\u4f9b\u79d1\u666e\u53c2\u8003\uff0c\u4e0d\u6784\u6210\u533b\u7597\u5efa\u8bae\u3002\u5982\u6709\u76ae\u80a4\u95ee\u9898\uff0c\u8bf7\u54a8\u8be2\u4e13\u4e1a\u76ae\u80a4\u79d1\u533b\u5e08\u3002<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>LED\u5149\u7597\u5982\u4f55\u901a\u8fc7\u5149\u751f\u7269\u8c03\u8282\u5f71\u54cd\u76ae\u80a4\uff1f\u672c\u6587\u57fa\u4e8e\u56fd\u9645\u6743\u5a01\u671f\u520a\u7814\u7a76\uff0c\u5ba2\u89c2\u89e3\u6790\u7ea2\u5149\u4fc3\u8fdb\u80f6\u539f\u86cb\u767d\u751f\u6210\u3001\u84dd\u5149\u6297\u83cc\u795b\u75d8\u7684\u79d1\u5b66\u673a\u5236\uff0c\u540c\u65f6\u63ed\u793a\u7597\u6548\u5dee\u5f02\u3001\u4f7f\u7528\u5c40\u9650\u53ca\u5b89\u5168\u6027\u95ee\u9898\uff0c\u5e2e\u52a9\u60a8\u5efa\u7acb\u7406\u6027\u8ba4\u77e5\u3002This article provides an evidence-based review of LED photobiomodulation effects on skin, covering the mechanisms of red light-induced collagen synthesis and blue light&#8217;s antibacterial action against acne, while addressing individual variability, safety profiles, and clinical 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